AJS1669 |CAS:1853130-05-8 Probechem Biochemicals

Chemical Structure : AJS1669

AJS1669 (AJS-1669;AJS 1669)

Catalog No.: PC-60250Not For Human Use, Lab Use Only.

AJS1669 (AJS-1669) is a novel potent, allosteric, orally available muscle glycogen synthase 1 (GYS1) activator with EC50 of 5.2 uM.

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Biological Activity

AJS1669 (AJS-1669) is a novel potent, allosteric, orally available muscle glycogen synthase 1 (GYS1) activator with EC50 of 5.2 uM; shows no activity for GYS2; improves glucose metabolism and reduces body fat mass in mice.

Physicochemical Properties

M.Wt	512.504
Formula	C26H20F2NO6S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(5-(((4',5'-difluoro-2'-(methylthio)-[1,1'-biphenyl]-4-yl)oxy)methyl)furan-2-carbonyl)-N-(furan-2-ylmethyl)glycinate

References

1. Nakano K, et al. Int J Mol Med. 2017 Apr;39(4):841-850.

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AJS1669 (AJS-1669;AJS 1669)

Biological Activity

Physicochemical Properties

References

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