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AJS1669 sodium

Chemical Structure : AJS1669 sodium

CAS No.: N/A

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AJS1669 sodium (AJS-1669 sodium, AJS 1669 sodium)

Catalog No.: PC-60251Not For Human Use, Lab Use Only.

AJS1669 sodium is a potent, allosteric, orally available muscle glycogen synthase 1 (GYS1) activator with EC50 of 5.2 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    AJS1669 sodium is a potent, allosteric, orally available muscle glycogen synthase 1 (GYS1) activator with EC50 of 5.2 uM.
    AJS1669 shows no activity for GYS2.
    AJS1669 improves glucose metabolism and reduces body fat mass in mice.

    Physicochemical Properties

    M.Wt 535.494
    Formula C26H20F2NNaO6S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-(5-(((4',5'-difluoro-2'-(methylthio)-[1,1'-biphenyl]-4-yl)oxy)methyl)furan-2-carbonyl)-N-(furan-2-ylmethyl)glycinate sodium salt

    References

    1. Nakano K, et al. Int J Mol Med. 2017 Apr;39(4):841-850.

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