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AJS1669 sodium

Chemical Structure : AJS1669 sodium

CAS No.: N/A

AJS1669 sodium (AJS-1669 sodium;AJS 1669 sodium)

Catalog No.: PC-60251Not For Human Use, Lab Use Only.

A novel potent, allosteric, orally available muscle glycogen synthase 1 (GYS1) activator with EC50 of 5.2 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A novel potent, allosteric, orally available muscle glycogen synthase 1 (GYS1) activator with EC50 of 5.2 uM; shows no activity for GYS2; improves glucose metabolism and reduces body fat mass in mice.

Physicochemical Properties

M.Wt 535.494
Formula C26H20F2NNaO6S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(5-(((4',5'-difluoro-2'-(methylthio)-[1,1'-biphenyl]-4-yl)oxy)methyl)furan-2-carbonyl)-N-(furan-2-ylmethyl)glycinate sodium salt

References

1. Nakano K, et al. Int J Mol Med. 2017 Apr;39(4):841-850.

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