Chemical Structure : AKU-005
Catalog No.: PC-20488Not For Human Use, Lab Use Only.
AKU-005 is a potent, dual MAGL/FAAH inhibitor with IC50 of 589 and 309 pM for MAGL in rat and mouse brain membrane respectively, inhibits rat and human FAAH with IC50 of 63 and 389 nM.
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AKU-005 is a potent, dual MAGL/FAAH inhibitor with IC50 of 589 and 309 pM for MAGL in rat and mouse brain membrane respectively, inhibits rat and human FAAH with IC50 of 63 and 389 nM.
M.Wt | 347.42 | |
Formula | C20H21N5O | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Niina Aaltonen, et al. Chem Biol. 2013 Mar 21;20(3):379-90.
2. Adriana Della Pietra, et al. J Headache Pain. 2023 Apr 11;24(1):38.
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