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ALB-127158

Chemical Structure : ALB-127158

CAS No.:

ALB-127158 (ALB127158A;CSTI-100)

Catalog No.: PC-61531Not For Human Use, Lab Use Only.

ALB-127158 is a potent (IC50=7 nM), selective, non-peptide antagonist of MCHR1 (Melanin-concentrating hormone receptor 1) for treatment of obesity..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ALB-127158 is a potent (IC50=7 nM), selective, non-peptide antagonist of MCHR1 (Melanin-concentrating hormone receptor 1) for treatment of obesity.

Obesity

Phase 1 Discontinued

Physicochemical Properties

M.Wt 414.509
Formula C25H26N4O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one

References

1. Moore NA, et al. Neurobiol Dis. 2014 Jan;61:47-54.

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