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ALG-000184

Chemical Structure : ALG-000184

CAS No.: 2495324-72-4

ALG-000184 (ALG000184)

Catalog No.: PC-23941Not For Human Use, Lab Use Only.

ALG-000184 is a highly soluble prodrug of the potent HBV capsid assembly modulator (CAM) ALG-001075 (HepG2.117, EC50=0.63 nM).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ALG-000184 is a highly soluble prodrug of the potent HBV capsid assembly modulator (CAM) ALG-001075 (HepG2.117, EC50=0.63 nM).

Physicochemical Properties

M.Wt 576.38
Formula C23H20FN4Na2O8P
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

sodium (2-(5-((3-cyano-4-fluorophenyl)carbamoyl)-1,2,4-trimethyl-1H-pyrrol-3-yl)-N-(3-ethynyloxetan-3-yl)-2-oxoacetamido)methyl phosphate

References

1. Vendeville S, et al. J Med Chem. 2024 Dec 12;67(23):21126-21142.

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