Catalog No.: PC-43307Not For Human Use, Lab Use Only.
ALS-8176 (Lumicitabine) is the 3',5'-di-O-isobutyryl prodrug of ALS-8112 5'-triphosphate (ALS-8112-TP), which is a potent, selective RSV polymerase inhibitor with IC50 of 20 nM.
ALS-8176 (Lumicitabine) is the 3',5'-di-O-isobutyryl prodrug of ALS-8112 5'-triphosphate (ALS-8112-TP), which is a potent, selective RSV polymerase inhibitor with IC50 of 20 nM.
ALS-8176 demonstrates good oral bioavailability and a high level of ALS-8112-TP in vivo, exhibits excellent anti-RSV efficacy and safety in vivo and clinical trials.
