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ALX-1393

Chemical Structure : ALX-1393

CAS No.: 949164-09-4

ALX-1393 (ALX 1393;ALX1393)

Catalog No.: PC-60446Not For Human Use, Lab Use Only.

ALX-1393 (ALX 1393, ALX1393) is a potent, specific GlyT2 inhibitor with Ki of <1 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

ALX-1393 (ALX 1393, ALX1393) is a potent, specific GlyT2 inhibitor with Ki of <1 uM.
ALX-1393 ameliorates dynamic and static mechanical allodynia in mice with herpetic or postherpetic pain, displays antinociceptive effects on in vivo.

Physicochemical Properties

M.Wt 395.43
Formula C23H22FNO4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2S)-2-amino-3-[(3-fluorophenyl)-(2-phenylmethoxyphenyl)methoxy]propanoic acid

References

1. Morita K, et al. J Pharmacol Exp Ther. 2008 Aug;326(2):633-45.

2. Nishikawa Y, et al. J Pharmacol Sci. 2010;112(3):352-60.

3. Jeong HJ, et al. Br J Pharmacol. 2010 Oct;161(4):925-35.

4. Eckle VS, et al. Neuroscience. 2013 Dec 3;253:165-71.

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