Chemical Structure : ALX5407
CAS No.: 571147-18-7
Catalog No.: PC-61461Not For Human Use, Lab Use Only.
ALX 5407 ((+)-NFPS) is a potent, selective GlyT1 inhibitor that demonstrates >10-fold greater activity in in vitro functional glycine reuptake assay than racemic (±)-NFPS.
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ALX 5407 ((+)-NFPS) is a is a potent, selective GlyT1 inhibitor that demonstrates >10-fold greater activity in in vitro functional glycine reuptake assay than racemic (±)-NFPS.
ALX 5407 ((+)-NFPS) is a induces a pattern of c-Fos immunoreactivity comparable with the atypical antipsychotic clozapine and enhanced prepulse inhibition of the acoustic startle response in mice.
M.Wt | 393.45 | |
Formula | C24H24FNO3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(R)-N-(3-([1,1'-biphenyl]-4-yloxy)-3-(4-fluorophenyl)propyl)-N-methylglycine |
1. Kinney GG, et al. J Neurosci. 2003 Aug 20;23(20):7586-91.
2. Huang B, et al. Cell Physiol Biochem. 2016;38(5):1952-62.
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