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AM-0216

Chemical Structure : AM-0216

CAS No.: 1202764-61-1

AM-0216 (AM0216)

Catalog No.: PC-35550Not For Human Use, Lab Use Only.

AM-0216 (AM0216) is a highly potent inhibitor of NF-κB inducing Kinase (NIK), example 294 in patent WO 2009158011 A1.

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    Biological Activity

    AM-0216 (AM0216) is a highly potent inhibitor of NF-κB inducing Kinase (NIK), example 294 in patent WO 2009158011 A1.

    Physicochemical Properties

    M.Wt 363.439
    Formula C19H17N5OS
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (R)-4-(1-(2-aminopyrimidin-4-yl)indolin-6-yl)-2-(thiazol-2-yl)but-3-yn-2-ol

    References

    1. Henry KL, et al. Sci Signal. 2018 Jul 31;11(541). pii: eaam8216.

    2. Example 294 in patent WO 2009158011 A1.

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