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Chemical Structure : AM-111
CAS No.: 1445179-97-4
Catalog No.: PC-47480Not For Human Use, Lab Use Only.
Brimapitide (KU002, D-JNKI-1, XG-102, AM-111) is a cell-permeable peptide inhibitor of JNK kinases.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $228 | In stock | |
| 10 mg | $368 | In stock | |
| 25 mg | $588 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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Brimapitide (KU002, D-JNKI-1, XG-102, AM-111) is a cell-permeable peptide inhibitor of JNK kinases.
Brimapitide blocks apoptotic JNK signaling in brain mitochondria.
Brimapitide decreases the expression of CD4(+) and CD8(+) cells, effects T-cell activation, differentiation, and migration in a murine model of chronic colitis.
Brimapitide prevents hearing loss from SC transection in the guinea pig model of PA-OM.
| M.Wt | 3822.44 | |
| Formula | C164H286N66O40 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
H2O: >50 mg/mL |
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| Chemical Name/SMILES |
NH2-DQSRPVQPFLNLTTPRKPRPPRRRQRRKKRG-COOH |
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1. Eshraghi AA, et al. Otol Neurotol. 2006 Jun;27(4):504-11.
2. Zhao Y, et al. Mol Cell Neurosci. 2012 Mar;49(3):300-10.
3. Kersting S, et al. J Inflamm Res. 2013 May 3;6:71-81.
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