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Chemical Structure : AM-1638
CAS No.: 1142214-62-7
Catalog No.: PC-60257Not For Human Use, Lab Use Only.
AM-1638 is a potent, orally bioavailable, full agonist of GPR40/FFA1 with EC50 of 0.16 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $288 | In stock | |
| 10 mg | $458 | In stock | |
| 25 mg | Get quote | ||
| 100 mg | Get quote |
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AM-1638 is a potent, orally bioavailable, full agonist of GPR40/FFA1 with EC50 of 0.16 uM.
AM-1638 stimulates GLP-1 and GIP secretion from intestinal enteroendocrine cells and increase GSIS from pancreatic islets.
AM-1638 enhances glucose control in mouse models of type 2 diabetes.
| M.Wt | 514.637 | |
| Formula | C33H35FO4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(S)-3-cyclopropyl-3-(3-((2-(5,5-dimethylcyclopent-1-en-1-yl)-2'-fluoro-5'-methoxy-[1,1'-biphenyl]-4-yl)methoxy)phenyl)propanoic acid |
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1. Brown SP, et al. ACS Med Chem Lett. 2012 Aug 15;3(9):726-30.
2. Luo J, et al. PLoS One. 2012;7(10):e46300.
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