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Chemical Structure : AM-8123
Catalog No.: PC-38137Not For Human Use, Lab Use Only.
AM-8123 (AM8123) is a small-molecule agonist of Apelin receptor (APJ, APLNR), inhibits forskolin-stimulated cAMP production (pEC50=9.44) and promoted Gα protein activation (pEC50=8.95).
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AM-8123 (AM8123) is a small-molecule agonist of Apelin receptor (APJ, APLNR), inhibits forskolin-stimulated cAMP production (pEC50=9.44) and promoted Gα protein activation (pEC50=8.95).
| M.Wt | 567.665 | |
| Formula | C27H33N7O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Brandon Ason, et al. JCI Insight. 2020 Apr 23;5(8):e132898.
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