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Chemical Structure : AM-9514
Catalog No.: PC-61099Not For Human Use, Lab Use Only.
A potent gucokinase (GK) activator with EC50 of 0.29 uM.
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A potent gucokinase (GK) activator with EC50 of 0.29 uM; exhibits excellent solubility, permeability, in vitro clearances and free fractions in plasma protein binding; demonstrates antidiabetic efficacy in vivo with no hypoglycemia.
| M.Wt | 359.43 | |
| Formula | C18H25N5O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Du X, et al. ACS Med Chem Lett. 2014 Nov 22;5(12):1284-9.
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