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AM4085

Chemical Structure : AM4085

CAS No.:

AM4085 (AM 4085)

Catalog No.: PC-21823Not For Human Use, Lab Use Only.

AM4085 is a potent, orally bioavailable lectin domain of FmLH antagonist with IC50 of 0.19 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

AM4085 is a potent, orally bioavailable lectin domain of FmLH antagonist with IC50 of 0.19 uM.
AM4085 a promising lead candidate worthy of further potency optimization and biological evaluation in advanced preclinical studies in the treatment of chronic urinary tract infections (UTIs) of the bladder and kidney.

Physicochemical Properties

M.Wt 459.39
Formula C21H21F4NO6
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-((2S,3R,4R,5R,6R)-2-((4'-fluoro-6-(trifluoromethyl)-[1,1'-biphenyl]-2-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide

References

1. Maddirala AR, et al. J Med Chem. 2024 Feb 3. doi: 10.1021/acs.jmedchem.3c02128.

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