Chemical Structure : AMG-337
CAS No.:
1173699-31-4
AMG-337
(AMG337;AMG 337)
Catalog No. : PC-45530Not For Human Use, Lab Use Only.
AMG-337 is a potent and selective inhibitor of MET with biochemical IC50 of 1 nM.
Packing Price Stock Quantity 5 mg $78 In stock 0 1 2 3 4 5 10 mg $128 In stock 0 1 2 3 4 5 25 mg $218 In stock 0 1 2 3 4 5 50 mg $358 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4553001
Biological Activity
AMG-337 is a potent and selective inhibitor of MET with biochemical IC50 of 1 nM.
Physicochemical Properties
M.Wt
463.4643
Formula
C23H22FN7O3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 30 mg/mL
Chemical Name/SMILES
1,6-Naphthyridin-5(6H)-one, 6-[(1R)-1-[8-fluoro-6-(1-methyl-1H-pyrazol-4-yl)-1,2,4-triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(2-methoxyethoxy)-
References
1. Boezio AA, et al. J Med Chem
2. Hughes PE, et al. Mol Cancer Ther
3. Du Z, et al. Mol Cancer Ther.
Contact Us
sales@probechem.com
