AMG-47a |CAS:882663-88-9 Probechem Biochemicals

Chemical Structure : AMG-47a

CAS No.: 882663-88-9

AMG-47a (AMG47a)

Catalog No.: PC-45449Not For Human Use, Lab Use Only.

AMG-47a is a potent Lck kinase inhibitor with IC50 of 0.2 nM, selectively reduces the levels of EGFP-KRASG12V protein but do not affect EGFP protein in cells.

Packing	Price	Stock
5 mg	$118	In stock
10 mg	$176	In stock
25 mg	$298	In stock
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Biological Activity

AMG-47a is a potent Lck kinase inhibitor with IC50 of 0.2 nM, selectively reduces the levels of EGFP-KRASG12V protein but do not affect EGFP protein in cells.

Physicochemical Properties

M.Wt	535.5601
Formula	C29H28F3N5O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	DMSO: ≥ 34 mg/mL
Chemical Name/SMILES	Benzamide, 4-methyl-3-[2-[[2-(4-morpholinyl)ethyl]amino]-6-quinazolinyl]-N-[3-(trifluoromethyl)phenyl]-

References

1. Carver J, et al. PLoS One. 2014 Aug 5;9(8):e103836.

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AMG-47a (AMG47a)

Biological Activity

Physicochemical Properties

References

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