Chemical Structure : AMG-47a
CAS No.: 882663-88-9
Catalog No.: PC-45449Not For Human Use, Lab Use Only.
AMG-47a is a potent Lck kinase inhibitor with IC50 of 0.2 nM, selectively reduces the levels of EGFP-KRASG12V protein but do not affect EGFP protein in cells.
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AMG-47a is a potent Lck kinase inhibitor with IC50 of 0.2 nM, selectively reduces the levels of EGFP-KRASG12V protein but do not affect EGFP protein in cells.
M.Wt | 535.5601 | |
Formula | C29H28F3N5O2 | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: ≥ 34 mg/mL |
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Chemical Name/SMILES |
Benzamide, 4-methyl-3-[2-[[2-(4-morpholinyl)ethyl]amino]-6-quinazolinyl]-N-[3-(trifluoromethyl)phenyl]- |
1. Carver J, et al. PLoS One. 2014 Aug 5;9(8):e103836.
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