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Chemical Structure : AMG650
CAS No.: 2410796-79-9
Catalog No.: PC-72904Not For Human Use, Lab Use Only.
AMG650 (Sovilnesib) is an oral, first in class, selective small molecule inhibitor of KIF18A with IC50 of 71 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $158 | In stock | |
| 10 mg | $248 | In stock | |
| 25 mg | $398 | In stock | |
| 50 mg | $598 | In stock | |
| 100 mg | Get quote |
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AMG650 (Sovilnesib) is an oral, first in class, selective small molecule inhibitor of KIF18A with IC50 of 71 nM.
KIF18A is a mitotic kinesin motor protein that regulates chromosome positioning during cell division and is overexpressed in a subset of human cancers.
| M.Wt | 564.653 | |
| Formula | C26H34F2N6O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-(2-(4,4-difluoropiperidin-1-yl)-6-methylpyrimidin-4-yl)-4-((2-hydroxyethyl)sulfonamido)-2-(6-azaspiro[2.5]octan-6-yl)benzamide |
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1, Patent WO2021211549.
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