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Chemical Structure : AMG747
Catalog No.: PC-60977Not For Human Use, Lab Use Only.
AMG747 (Tilapertin) is a nanomolar potent, selective, and orally bioavailable glycine transporter type-1 (GlyT1) inhibitor for the treatment of negative symptoms associated with schizophrenia.
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AMG747 (Tilapertin) is a nanomolar potent, selective, and orally bioavailable glycine transporter type-1 (GlyT1) inhibitor for the treatment of negative symptoms associated with schizophrenia.
AMG747 (Tilapertin) dose-dependently increases cerebrospinal fluid (CSF) glycine concentration in rats and humans.
| M.Wt | 378.395 | |
| Formula | C20H21F3N2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Dunayevich E, et al. Schizophr Res. 2017 Apr;182:90-97.
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