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Chemical Structure : AMG 837
Catalog No.: PC-43813Not For Human Use, Lab Use Only.
AMG 837 is a potent partial GPR40 (FFA1) agonist (EC50=13 nM for hGPR40).
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AMG 837 is a potent partial GPR40 (FFA1) agonist (EC50=13 nM for hGPR40).
AMG 837 exhibits superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents; orally bioactive.
| M.Wt | 438.4384 | |
| Formula | C26H21F3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Houze JB, et al. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1267-70.
2. Lin DC, et al. PLoS One. 2011;6(11):e27270.
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