Chemical Structure : ANT3310 sodium
CAS No.: 2410688-61-6
Catalog No.: PC-24831Not For Human Use, Lab Use Only.
ANT3310 sodium (Pilabactam) is a potent, covalent broad-spectrum serine β-Lactamase inhibitor with IC50 of 1-175 nM against a panel of serine β-Lactamases.
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ANT3310 sodium (Pilabactam) is a potent, covalent broad-spectrum serine β-Lactamase inhibitor with IC50 of 1-175 nM against a panel of serine β-Lactamases.
ANT3310 is a very good inhibitor of OXA-23, as well as OXA-48, but not avibactam.
ANT3310 is equipotent against KPC- and OXA-CRE while superior against OXA-CRAB.
ANT3310 is effective against CREs and A. baumannii strains and is efficacious in mouse infection models.
M.Wt | 262.19 | |
Formula | C6H8FN2NaO5S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
sodium (2R,5R)-2-fluoro-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl sulfate |
1. Davies DT, et al. J Med Chem. 2020 Dec 24;63(24):15802-15820.
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