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Chemical Structure : APD916
Catalog No.: PC-61562Not For Human Use, Lab Use Only.
APD916 is a potent and selective antagonist of the H3 receptor with Ki of 0.7 nM for rH3R.
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APD916 is a potent and selective antagonist of the H3 receptor with Ki of 0.7 nM for rH3R.
APD916 increases wakefulness in rodents as measured by polysomnography with a duration of effect consistent with its pharmacokinetic properties.
| M.Wt | 401.565 | |
| Formula | C23H31NO3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Semple G, et al. Bioorg Med Chem Lett. 2012 Jan 1;22(1):71-5.
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