APX2039 | Gwt1 inhibitor | Probechem Biochemicals

Chemical Structure : APX2039

CAS No.: 2342606-49-7

Catalog No.: PC-23299Not For Human Use, Lab Use Only.

APX2039 is a novel potent small molecule inhibitor of fungal Gwt1, has MIC of 0.008-0.031 ug/ mL against C. neoformans, C. gattii, Candida albicans.

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Biological Activity

APX2039 is a novel potent small molecule inhibitor of fungal Gwt1, has MIC of 0.008-0.031 ug/ mL against C. neoformans, C. gattii, Candida albicans.

M.Wt	362.36
Formula	C20H15FN4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-[3-[[4-[(6-Fluoro-2-pyridinyl)oxy]phenyl]methyl]-5-isoxazolyl]-2-pyridinamine

1. Giamberardino CD, et al. mBio. 2022 Dec 20;13(6):e0234722.

2. Yu CH, et al.mBio. 2021 Dec 21;12(6):e0231321.

3. Karen Joy Shaw, et al. Antimicrob Agents Chemother. 2018 Jul 27;62(8):e00523-18.