Catalog No.: PC-25934Not For Human Use, Lab Use Only.
AR-R17779 hydrochloride is a potent, selective and full alpha7 nicotinic acetylcholine receptor (α7nAChR) agonist with Ki of 92 nM, >150-fold selective over α4β2 subtype.
AR-R17779 hydrochloride is a potent, selective and full alpha7 nicotinic acetylcholine receptor (α7nAChR) agonist with Ki of 92 nM, >150-fold selective over α4β2 subtype. AR-R17779 hydrochloride improves learning in two radial-arm maze tasks and reversed working memory impairment caused by fimbria-fornix sections. AR-R17779 hydrochloride also has anxiolytic activity. AR-R17779 hydrochloride can reduce inflammation by activating antiinflammatory cholinergic (vagal) pathways.
