AR234958 | Mas1 agonist | Probechem Biochemicals

Chemical Structure : AR234958

AR234958 (AR-234958)

Catalog No.: PC-26492Not For Human Use, Lab Use Only.

AR234958 is a selective pharmacological activator of orphan GPCR Mas1 with pEC50 of 6.71, demonstrates superior efficacy compared to the peptide ligands NPFF, Ang-(1-7).

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Biological Activity

AR234958 is a selective pharmacological activator of orphan GPCR Mas1 with pEC50 of 6.71, demonstrates superior efficacy compared to the peptide ligands NPFF, Ang-(1-7).

Physicochemical Properties

M.Wt	572.63
Formula	C28H30F2N4O5S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(4-fluorophenyl)-4-((4-(3-fluorophenyl)-1-((2-methoxy-4-nitrophenyl)sulfonyl)pyrrolidin-3-yl)methyl)piperazine

References

1. Zhang Y, et al. EMBO J. 2026 Mar 30. doi: 10.1038/s44318-026-00764-6.

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AR234958 (AR-234958)

Biological Activity

Physicochemical Properties

References

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