ARC-3140 | CK2 inhibitor | Probechem Biochemicals

Chemical Structure : ARC-3140

ARC-3140 (ARC3140)

Catalog No.: PC-22273Not For Human Use, Lab Use Only.

ARC-3140 is a potent, selective bisubstrate inhibitor of protein kinase CK2 (Casein kinase II) with Ki of 84 pM, addressing the ATP site and the substrate-binding site of CK2, interferes with both sub-interfaces of the bipartite CK2α/CK2β interaction.

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Biological Activity

Physicochemical Properties

M.Wt	1582.63
Formula	C45H58I4N10O21
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(8-(4,5,6,7-tetraiodo-1H-benzo[d]imidazol-1-yl)octanoyl)-D-aspartyl-L-aspartyl-L-aspartyl-L-aspartyl-L-aspartyl-L-aspartyl-L-lysine

References

1. Markus Pietsch, et al. Bioorg Chem. 2020 Mar:96:103608.

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ARC-3140 (ARC3140)

Biological Activity

Physicochemical Properties

References

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