ARRY-380 analog | HER2 inhibitor| Probechem Biochemicals

Chemical Structure : ARRY-380 analog

CAS No.: 937265-83-3

Catalog No.: PC-42641Not For Human Use, Lab Use Only.

An analog of ARRY-380, a potent and selective HER2 inhibitor with IC50 of 8 nM.

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Biological Activity

An analog of ARRY-380, a potent and selective HER2 inhibitor with IC50 of 8 nM; displays 500-fold selectivity over EGFR.

M.Wt	569.6342
Formula	C29H27N7O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-Quinazolinamine, 6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-

1. Patent WO2015153959A2.