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ARRY-380 analog

Chemical Structure : ARRY-380 analog

CAS No.: 937265-83-3

ARRY-380 analog (ARRY380 analog ;ARRY 380 analog)

Catalog No.: PC-42641Not For Human Use, Lab Use Only.

An analog of ARRY-380, a potent and selective HER2 inhibitor with IC50 of 8 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

An analog of ARRY-380, a potent and selective HER2 inhibitor with IC50 of 8 nM; displays 500-fold selectivity over EGFR.

Physicochemical Properties

M.Wt 569.6342
Formula C29H27N7O4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-Quinazolinamine, 6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-

References

1. Patent WO2015153959A2.

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