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Chemical Structure : ARUK3001185
CAS No.: 2411969-39-4
Catalog No.: PC-72827Not For Human Use, Lab Use Only.
ARUK3001185 is a potent, selective, brain-penetrant inhibitor of Wnt-deactivating enzyme Notum carboxylesterase activity with IC50 of 6.7 nM in OPTS biochemical assay.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $278 | In stock | |
| 25 mg | $458 | In stock | |
| 50 mg | $728 | In stock | |
| 100 mg | Get quote |
Bulk size, bulk discount!
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| M.Wt | 282.047 | |
| Formula | C9H4Cl2F3N3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
1-(2,4-dichloro-3-(trifluoromethyl)phenyl)-1H-1,2,3-triazole |
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1. William Mahy, et al. J Med Chem. 2020 Nov 12;63(21):12942-12956.
2. Elliott D Bayle, et al. J Med Chem. 2021 Apr 22;64(8):4289-4311.
3. Zhao Y, et al. Future Med Chem. 2021 Jun;13(11):1001-1015.
4. University of Oxford: WO2020043866 (2020).
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