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AS-48

Chemical Structure : AS-48

CAS No.: 865837-21-4

AS-48 (Measles virus entry inhibitor)

Catalog No.: PC-73391Not For Human Use, Lab Use Only.

AS-48 is a specific, small-molecule measles virus (MeV) entry inhibitor with IC50 of 0.6 uM agianst MV-KS.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    AS-48 is a specific, small-molecule measles virus (MeV) entry inhibitor with IC50 of 0.6 uM agianst MV-KS.
    AS-48 did not inhibit HPIV-2 and prevent membrane fusion induced by HIV type 1.
    AS-48 demonstrated potency against a representative panel of primary MV strains with IC50 of 0.6-3.0 uM.

    Physicochemical Properties

    M.Wt 299.286
    Formula C15H13N3O4
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    4-nitro-2-(2-phenylacetamido)benzamide

    References

    1. Richard K Plemper, et al. Antimicrob Agents Chemother. 2005 Sep;49(9):3755-61.

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