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Chemical Structure : AS1604498
Catalog No.: PC-61000Not For Human Use, Lab Use Only.
AS1604498 is a potent nicotinamide phosphoribosyl transferase (NAMPT) inhibitor with IC50 of 44 nM.
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AS1604498 is a potent nicotinamide phosphoribosyl transferase (NAMPT) inhibitor with IC50 of 44 nM.
AS1604498 inhibits THP-1 and K562 cell line growth with the IC50 of 198 nM and 673 nM, respectively.
AS1604498 reduces intracellular NAD and induces apoptosis.
| M.Wt | 319.364 | |
| Formula | C19H17N3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Takeuchi M, et al. Biol Pharm Bull. 2014;37(1):31-6.
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