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AS2575959

Chemical Structure : AS2575959

CAS No.: 1616871-34-1

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AS2575959 (AS 2575959, AS-2575959)

Catalog No.: PC-60999Not For Human Use, Lab Use Only.

AS2575959 is a novel potent, specific, orally available GPR40 agonist that influences glucose-dependent insulin secretion both in vitro pancreas β-cell-derived cells and in vivo.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    AS2575959 is a novel potent, specific, orally available GPR40 agonist that influences glucose-dependent insulin secretion both in vitro pancreas β-cell-derived cells and in vivo.
    AS2575959 demonstrates a synergistic effect on insulin secretion and plasma GLP-1 level combined with DPP-IV inhibitor.

    Physicochemical Properties

    M.Wt 554.615
    Formula C32H35NaO7
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    Sodium [(3S)-6-({4'-[(3S)-3,4-dihydroxybutoxy]-2,2',6'-trimethyl[1,1'-biphenyl]-3-yl}methoxy)-3H-spiro[1-benzofuran-2,1'-cyclopropan]-3-yl]acetate

    References

    1. Tanaka H, et al. Life Sci. 2014 Jan 17;94(2):115-21.

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