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AS3580239

Chemical Structure : AS3580239

CAS No.:

AS3580239

Catalog No.: PC-27340Not For Human Use, Lab Use Only.

AS3580239 is a positive allosteric modulator of skeletal muscle-type nicotinic acetylcholine receptor (m-nAChR), increases ACh-induced current in human myoblasts.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

AS3580239 is a positive allosteric modulator of skeletal muscle-type nicotinic acetylcholine receptor (m-nAChR), increases ACh-induced current in human myoblasts.

Physicochemical Properties

M.Wt 649.62
Formula C27H22F3N5O7S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

7-(2,3-dihydroxypropoxy)-4-hydroxy-2-methyl-N-(5-(2-phenylpyrimidin-5-yl)-4-(trifluoromethyl)thiazol-2-yl)-2H-benzo[e][1,2]thiazine-3-carboxamide 1,1-dioxide

References

1. Saito, A. et al. Biophys. Res. Commun. 668, 27-34 (2023).

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