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Chemical Structure : AT-101
CAS No.: 866541-93-7
Catalog No.: PC-44439Not For Human Use, Lab Use Only.
AT-101 ((R)-(-)-Gossypol acetic acid) is a natural phenol that permeates cells and acts as an inhibitor for several dehydrogenase enzymes such as lactate dehydrogenase, NAD-linked enzymes.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $128 | In stock | |
| 25 mg | $198 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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AT-101 ((R)-(-)-Gossypol acetic acid) is a natural phenol that permeates cells and acts as an inhibitor for several dehydrogenase enzymes such as lactate dehydrogenase, NAD-linked enzymes.
AT-101 a BH3 mimetic that binds and antagonizes anti-apoptotic effect of Bcl-2 family proteins, inhibits tumor growth in Wus1-bearing mice.
| M.Wt | 578.6064 | |
| Formula | C32H34O10 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO; Methanol: 7.75 mg/mL |
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| Chemical Name/SMILES |
[2,2'-Binaphthalene]-8,8'-dicarboxaldehyde, 1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)-, (2R)-, compd. with acetic acid (1:1) |
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1. Lin J, et al. Oncol Rep. 2013 Aug;30(2):731-8.
2. Ciereszko A, et al. Aquat Toxicol. 2000,49(3):181-187.
3. Ferdek PE, et al. Cell Death Dis. 2017 Mar 2;8(3):e2640.
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