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ATA-101

Chemical Structure : ATA-101

CAS No.: 639489-84-2

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ATA-101 (Tc-5619, Bradanicline)

Catalog No.: PC-73326Not For Human Use, Lab Use Only.

ATA-101 (Tc-5619, Bradanicline) is a potent, highly selective, CNS-penetrant α7 nicotinic receptor (α7 nAChR) agonist.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    ATA-101 (Tc-5619, Bradanicline) is a potent, highly selective, CNS-penetrant α7 nicotinic receptor (α7 nAChR) agonist.
    ATA-101 is orally bioavailable, dose-dependently inhibits coughing in guinea pigs evoked by citric acid and bradykinin.

    Physicochemical Properties

    M.Wt 361.445
    Formula C22H23N3O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-((2S,3R)-2-(pyridin-3-ylmethyl)quinuclidin-3-yl)benzofuran-2-carboxamide

    References

    1. Brendan J Canning, et al. J Pharmacol Exp Ther. 2022 Feb;380(2):94-103.

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