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ATF3W-aeg peptide

Chemical Structure : ATF3W-aeg peptide

CAS No.:

ATF3W-aeg peptide (ATF3W_aeg)

Catalog No.: PC-21905Not For Human Use, Lab Use Only.

ATF3W-aeg peptide is a selective, peptide inhibitor of activating transcription factor 3 (ATF3) with high affinity (Kd=151 nM), increases CCL4 expression levels in human macrophages.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    ATF3W-aeg peptide is a selective, peptide inhibitor of activating transcription factor 3 (ATF3) with high affinity (Kd=151 nM), increases CCL4 expression levels in human macrophages.
    Activating transcription factor 3 (ATF3) is an activation transcription factor/cyclic adenosine monophosphate (cAMP) responsive element-binding (CREB) protein family member.
    ATF3 is a stress-induced transcription factor implicated in the modulation of immunity and oncogenesis in various cancers, including prostate, breast, colon, lung, and liver cancers.

    Physicochemical Properties

    M.Wt
    Formula
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    ELAALEQKAYALKQENAALEKEVAALEQKIAALK

    References

    1. Miao Yu, et al. ACS Chem Biol. 2024 Feb 27. doi: 10.1021/acschembio.3c00779.

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