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ATF3W-aeg peptide

Chemical Structure : ATF3W-aeg peptide

CAS No.:

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ATF3W-aeg peptide (ATF3W_aeg)

Catalog No.: PC-21905Not For Human Use, Lab Use Only.

ATF3W-aeg peptide is a selective, peptide inhibitor of activating transcription factor 3 (ATF3) with high affinity (Kd=151 nM), increases CCL4 expression levels in human macrophages.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ATF3W-aeg peptide is a selective, peptide inhibitor of activating transcription factor 3 (ATF3) with high affinity (Kd=151 nM), increases CCL4 expression levels in human macrophages.
Activating transcription factor 3 (ATF3) is an activation transcription factor/cyclic adenosine monophosphate (cAMP) responsive element-binding (CREB) protein family member.
ATF3 is a stress-induced transcription factor implicated in the modulation of immunity and oncogenesis in various cancers, including prostate, breast, colon, lung, and liver cancers.

Physicochemical Properties

M.Wt
Formula
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

ELAALEQKAYALKQENAALEKEVAALEQKIAALK

References

1. Miao Yu, et al. ACS Chem Biol. 2024 Feb 27. doi: 10.1021/acschembio.3c00779.

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