ATPCA hydrochloride

Chemical Structure : ATPCA hydrochloride

CAS No.: 185444-92-2

Catalog No.: PC-26892Not For Human Use, Lab Use Only.

ATPCA hydrochloride is a potent substrate-inhibitor of the betaine/GABA transporter 1 (BGT1) with IC50 of 2.5 uM (hBGT1), shows >15-fold selective over hGAT2 and hGAT3, no acitivty against hGAT1.

Packing	Price	Stock
10 mg	$78	In stock
25 mg	$128	In stock
50 mg	$198	In stock
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Biological Activity

ATPCA hydrochloride is a potent substrate-inhibitor of the betaine/GABA transporter 1 (BGT1) with IC50 of 2.5 uM (hBGT1), shows >15-fold selective over hGAT2 and hGAT3, no acitivty against hGAT1.

Physicochemical Properties

M.Wt	179.60
Formula	C5H10ClN3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Amino-1,4,5,6-tetrahydropyrimidine-5-carboxylic acid hydrochloride

References

1. Kickinger S, et al. Sci Rep. 2020 Aug 3;10(1):12992.

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