Chemical Structure : AU403
Catalog No.: PC-27063Not For Human Use, Lab Use Only.
AU403 is a potent, isoform-selective LXRβ/PPARδ dual agonist with EC50 of 45/40 nM respectively, significantly improves cognitive functions and reduces amyloid-β plaque burden in 3xTg-AD animal model of Alzheimer's disease.
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AU403 is a potent, isoform-selective LXRβ/PPARδ dual agonist with EC50 of 45/40 nM respectively, significantly improves cognitive functions and reduces amyloid-β plaque burden in 3xTg-AD animal model of Alzheimer's disease.
| M.Wt | 403.38 | |
| Formula | C22H17F4NO2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Meenakshi Singh, et al. ACS Chem Biol. 2026 Jun 15. doi: 10.1021/acschembio.6c00240.

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