Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Nuclear Receptor/Transcription Factor-Liver X Receptor (LXR)-AU403
AU403

Chemical Structure : AU403

CAS No.:

AU403 (AU-403)

Catalog No.: PC-27063Not For Human Use, Lab Use Only.

AU403 is a potent, isoform-selective LXRβ/PPARδ dual agonist with EC50 of 45/40 nM respectively, significantly improves cognitive functions and reduces amyloid-β plaque burden in 3xTg-AD animal model of Alzheimer's disease.

Packing Price Stock Quantity
50 mg Get quote
100 mg Get quote
250 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

AU403 is a potent, isoform-selective LXRβ/PPARδ dual agonist with EC50 of 45/40 nM respectively, significantly improves cognitive functions and reduces amyloid-β plaque burden in 3xTg-AD animal model of Alzheimer's disease.

Physicochemical Properties

M.Wt 403.38
Formula C22H17F4NO2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-((((3-fluoro-3'-(trifluoromethyl)-[1,1'-biphenyl]-2-yl)methyl)amino)methyl)benzoic acid

References

1. Meenakshi Singh, et al. ACS Chem Biol. 2026 Jun 15. doi: 10.1021/acschembio.6c00240.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: