Chemical Structure : AUNP-12
CAS No.: 1353563-85-5
Catalog No.: PC-35694Not For Human Use, Lab Use Only.
AUNP-12 (Aurigene-012) is a PD-1 inhibitor peptide, blocks the PD-1/PD-L1, PD-1/PD-L2 and PD-L1/CD80 pathways.
Packing | Price | Stock | Quantity |
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5 mg | $238 | In stock | |
10 mg | $378 | In stock | |
25 mg | $578 | In stock | |
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100 mg | Get quote |
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AUNP-12 (Aurigene-012) is a PD-1 inhibitor peptide, blocks the PD-1/PD-L1, PD-1/PD-L2 and PD-L1/CD80 pathways.
AUNP-12 is highly effective in antagonizing PD-1 signaling, with desirable in vivo exposure upon subcutaneous dosing.
AUNP-12 inhibits tumor growth and metastasis in preclinical models of cancer and is well tolerated with no overt toxicity at any of the tested doses.
M.Wt | 3261.55 | |
Formula | 3261.6 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
N2,N6-bis(L-seryl-L-asparaginyl-L-threonyl-L-seryl-L-α-glutamyl-L-seryl-L-phenylalanyl)-L-lysyl-L-phenylalanyl-L-arginyl-L-valyl-L-threonyl-L-glutaminyl-L-leucyl-L-alanyl-L-prolyl-L-lysyl-L-alanyl-L-glutaminyl-L-isoleucyl-L-lysyl-L-α-glutamine |
1. Gao, Y.; Chen, Y.; Qi, Y.; Liu, B. PD-L1 Affinity Peptide with Anti-Tumour Activity and Application Thereof. CN103304638A, 2013.
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