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Chemical Structure : AUTEN-99 hydrobromide
Catalog No.: PC-70066Not For Human Use, Lab Use Only.
A small molecule autophagy enhancer that inhibit the myotubularin-related phosphatase MTMR14/Jumpy.
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AUTEN-99 hydrobromide is a small molecule autophagy enhancer that inhibit the myotubularin-related phosphatase MTMR14/Jumpy.
AUTEN-99 induces autophagic flux and promotes cell survival in mammalian cell cultures.
AUTEN-99 increases the number of autophagic structures in mice and Drosophila, and effectively penetrates through a blood-brain barrier model; impedes the progression of neurodegenerative symptoms in Drosophila models of Parkinson's and Huntington's diseases.
| M.Wt | 359.285 | |
| Formula | C17H15BrN2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Kovács T, et al. Sci Rep. 2017 Feb 16;7:42014.
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