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AVG-388

Chemical Structure : AVG-388

CAS No.: 2903486-95-1

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AVG-388 (AVG388)

Catalog No.: PC-47082Not For Human Use, Lab Use Only.

AVG-388 is a potent, allosteric, orally efficacious inhibitor of respiratory syncytial virus (RSV) RNA synthesis, potently blocks RSV RNA-dependent RNA polymerase (RdRP) bioactivity, exhibits strong antiviral efficacy in vivo.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    AVG-388 is a potent, allosteric, orally efficacious inhibitor of respiratory syncytial virus (RSV) RNA synthesis, potently blocks RSV RNA-dependent RNA polymerase (RdRP) bioactivity, exhibits strong antiviral efficacy in vivo.

    Physicochemical Properties

    M.Wt 629.443
    Formula C27H16F9N5O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-(3,5-difluoropyridin-2-yl)-4-methyl-1-(2,3,5,6-tetrafluoro-4-methoxybenzyl)-5-((6-(trifluoromethyl)pyridin-2-yl)methyl)-1,2-dihydro-3H-pyrazolo[4,3-c]pyridine-3,6(5H)-dione

    References

    1. Julien Sourimant, et al. Sci Adv. 2022 Jun 24;8(25):eabo2236.

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