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AX-000

Chemical Structure : AX-000

CAS No.: 340014-88-2

AX-000 (AX000;AX 000)

Catalog No.: PC-60399Not For Human Use, Lab Use Only.

A hit compound that inhibits the proliferation of human peripheral blood T cells stimulated with anti-CD3 with IC50 of <10 nM, inhibits TCR-Nck interaction..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A hit compound that inhibits the proliferation of human peripheral blood T cells stimulated with anti-CD3 with IC50 of <10 nM, inhibits TCR-Nck interaction.

Physicochemical Properties

M.Wt 381.519
Formula C27H27NO
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-((2,4-diphenyl-4H-chromen-3-yl)methyl)piperidine

References

1. Borroto A, et al. Sci Transl Med. 2016 Dec 21;8(370):370ra184.

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