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AX-000

Chemical Structure : AX-000

CAS No.: 340014-88-2

AX-000 (AX000, AX 000)

Catalog No.: PC-60399Not For Human Use, Lab Use Only.

AX-000 is a hit compound that inhibits the proliferation of human peripheral blood T cells stimulated with anti-CD3 with IC50 of <10 nM, inhibits TCR-Nck interaction.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    AX-000 is a hit compound that inhibits the proliferation of human peripheral blood T cells stimulated with anti-CD3 with IC50 of <10 nM, inhibits TCR-Nck interaction.

    Physicochemical Properties

    M.Wt 381.519
    Formula C27H27NO
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    1-((2,4-diphenyl-4H-chromen-3-yl)methyl)piperidine

    References

    1. Borroto A, et al. Sci Transl Med. 2016 Dec 21;8(370):370ra184.

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