AX-000 | TCR-Nck inhibitor | Probechem Biochemicals

Chemical Structure : AX-000

AX-000 (AX000, AX 000)

Catalog No.: PC-60399Not For Human Use, Lab Use Only.

AX-000 is a hit compound that inhibits the proliferation of human peripheral blood T cells stimulated with anti-CD3 with IC50 of <10 nM, inhibits TCR-Nck interaction.

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Biological Activity

AX-000 is a hit compound that inhibits the proliferation of human peripheral blood T cells stimulated with anti-CD3 with IC50 of <10 nM, inhibits TCR-Nck interaction.

Physicochemical Properties

M.Wt	381.519
Formula	C27H27NO
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-((2,4-diphenyl-4H-chromen-3-yl)methyl)piperidine

References

1. Borroto A, et al. Sci Transl Med. 2016 Dec 21;8(370):370ra184.

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AX-000 (AX000, AX 000)

Biological Activity

Physicochemical Properties

References

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