Chemical Structure : AX20017
CAS No.: 329221-38-7
Catalog No.: PC-73194Not For Human Use, Lab Use Only.
AX20017 is a highly selective inhibitor of Mycobacterium tuberculosis protein kinase G (PknG) with IC50 of 0.39 uM.
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AX20017 is a highly selective inhibitor of Mycobacterium tuberculosis protein kinase G (PknG) with IC50 of 0.39 uM.
AX20017 is buried deep within the adenosine-binding site, targeting an active conformation of the kinase domain.
AX20017 is a reference to determine candidate compounds that can act as potential inhibitors for PknG as anti-mycobacterium tuberculosis compounds.
M.Wt | 268.37 | |
Formula | C13H20N2O2S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
2-(Cyclopropanecarboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide |
1. Walburger A, et al. Science. 2004 Jun 18;304(5678):1800-4.
2. Scherr N, et al. Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12151-6.
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