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Chemical Structure : AZ-27
Catalog No.: PC-60359Not For Human Use, Lab Use Only.
AZ-27 (AZ27) is a potent non-nucleoside RSV L-protein polymerase inhibitor with EC50 of 0.01 uM and 1.3 uM for RSV A2 and RSV B-WST, respectively.
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AZ-27 (AZ27) is a potent non-nucleoside RSV L-protein polymerase inhibitor with EC50 of 0.01 uM and 1.3 uM for RSV A2 and RSV B-WST, respectively.
AZ27 exhibits high potency against the RSV A subtype (average EC50=24±9 nM) than against the B subtype (average EC50=1.0±0.28 uM).
AZ-27 (AZ27) shows no cytotoxicity.
| M.Wt | 633.767 | |
| Formula | C36H35N5O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Tiong-Yip CL, et al. Antimicrob Agents Chemother. 2014 Jul;58(7):3867-73.
2. Noton SL, et al. J Virol. 2015 Aug;89(15):7786-98.
3. Deval J, et al. PLoS One. 2016 May 10;11(5):e0154097.
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