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Chemical Structure : AZ-66
Catalog No.: PC-21111Not For Human Use, Lab Use Only.
AZ-66 is a highly potent S1R/S2R antagonist with Ki of 0.31/1.76 nM, respectively.
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AZ-66 is a highly potent S1R/S2R antagonist with Ki of 0.31/1.76 nM, respectively.
AZ-66 demonstrated anti-allodynic effects in the CCI assay.
AZ-66 exhibited antinociception with an ED50 value of 11.6 (8.29–15.6) mg/kg, i.p. against a thermal nociceptive stimulus in the mouse 55°C warm-water tail-withdrawal assay.
| M.Wt | 404.59 | |
| Formula | C23H33FN2OS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Cirino TJ, et al. Front Pharmacol. 2019 Jun 14;10:678.
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