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AZ13792138

Chemical Structure : AZ13792138

CAS No.:

AZ13792138 (AZ 13792138)

Catalog No.: PC-72026Not For Human Use, Lab Use Only.

AZ13792138 is a highly potent, selective inhibitor of MTH1 (NUDT1) with Kd/IC50 of 0.4/0.5 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    AZ13792138 is a highly potent, selective inhibitor of MTH1 (NUDT1) with Kd/IC50 of 0.4/0.5 nM.

    Physicochemical Properties

    M.Wt 358.15
    Formula C17H20N5O4
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    20-(Methylamino)-4,5,7,8-tetrahydro-15H-2,19-(azenometheno)-14,10-(metheno)imidazo[5,1-d][1,12,15,3,5]trioxadiazacycloheptadecin-17(18H)-one

    References

    1. Jason G Kettle, et al. J Med Chem. 2016 Mar 24;59(6):2346-61.

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