AZ3 | PI4KB inhibitor | Probechem Biochemicals

Chemical Structure : AZ3

AZ3 (PI4KB inhibitor 3)

Catalog No.: PC-73080Not For Human Use, Lab Use Only.

AZ3 (PI4KB inhibitor 3) is a seletive PI4KB inhibitor with pIC50 of 7.8, shows good lipid kinase selectivity (pIC50 5.1, 4.7 and 4.0 for PI4Kα, PI3Kα and PIP5Kγ respectively).

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Biological Activity

AZ3 (PI4KB inhibitor 3) is a seletive PI4KB inhibitor with pIC50 of 7.8, shows good lipid kinase selectivity (pIC50 5.1, 4.7 and 4.0 for PI4Kα, PI3Kα and PIP5Kγ respectively).

Physicochemical Properties

M.Wt	499.604
Formula	C23H25N5O4S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-1-acetyl-N-(4-methyl-5-(6-(phenylsulfonamido)pyridin-2-yl)thiazol-2-yl)piperidine-2-carboxamide

References

1. Michael J Waring, et al. Chem Commun (Camb). 2014 May 25;50(40):5388-90.

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AZ3 (PI4KB inhibitor 3)

Biological Activity

Physicochemical Properties

References

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