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Chemical Structure : AZ 4800
Catalog No.: PC-62920Not For Human Use, Lab Use Only.
AZ 4800 is a potent γ-secretase modulator that reduces Aβ40 and Aβ42 levels in HEK/APPswe cells with IC50 of 26 nM and 60 nM, also decreases Aβ39, whereas increases both Aβ37 and Aβ38..
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AZ 4800 is a potent γ-secretase modulator that reduces Aβ40 and Aβ42 levels in HEK/APPswe cells with IC50 of 26 nM and 60 nM, also decreases Aβ39, whereas increases both Aβ37 and Aβ38.
| M.Wt | 435.528 | |
| Formula | C24H29N5O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Borgegard T, et al. J Biol Chem. 2012 Apr 6;287(15):11810-9.
2. Strömberg K, et al. FEBS J. 2015 Jan;282(1):65-73.
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