AZ6421 | ER PROTAC | Probechem Biochemicals

Chemical Structure : AZ6421

AZ6421 (AZ'6421)

Catalog No.: PC-49352Not For Human Use, Lab Use Only.

AZ'6421 is a Protcolysis Targeting Chimera (PROTAC) to selectively degrade estrogen receptor, shows ER binding and ER degradation with IC50 and DC50 values of 0.6 nM and 0.4 nM, respectively in MCF-7 cell lines.

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Biological Activity

AZ'6421 is a Protcolysis Targeting Chimera (PROTAC) to selectively degrade estrogen receptor, shows ER binding and ER degradation with IC50 and DC50 values of 0.6 nM and 0.4 nM, respectively in MCF-7 cell lines.

Physicochemical Properties

M.Wt	975.17
Formula	C52H65F3N6O7S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES

References

1. Patent WO2019123367A1.

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AZ6421 (AZ'6421)

Biological Activity

Physicochemical Properties

References

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