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AZ6421

Chemical Structure : AZ6421

CAS No.: 2361115-35-5

AZ6421 (AZ'6421)

Catalog No.: PC-49352Not For Human Use, Lab Use Only.

AZ'6421 is a Protcolysis Targeting Chimera (PROTAC) to selectively degrade estrogen receptor, shows ER binding and ER degradation with IC50 and DC50 values of 0.6 nM and 0.4 nM, respectively in MCF-7 cell lines.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

AZ'6421 is a Protcolysis Targeting Chimera (PROTAC) to selectively degrade estrogen receptor, shows ER binding and ER degradation with IC50 and DC50 values of 0.6 nM and 0.4 nM, respectively in MCF-7 cell lines.

Physicochemical Properties

M.Wt 975.17
Formula C52H65F3N6O7S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

References

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