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AZ7550

Chemical Structure : AZ7550

CAS No.: 1421373-99-0

AZ7550 (AZ-7550)

Catalog No.: PC-28295Not For Human Use, Lab Use Only.

AZ7550 is a bioactive metabolite of osimertinib, potently inhibits insulin-like growth factor-1 receptor (IGF-1R) with IC50 of 1.6 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

AZ7550 is a bioactive metabolite of osimertinib, potently inhibits insulin-like growth factor-1 receptor (IGF-1R) with IC50 of 1.6 uM.

Physicochemical Properties

M.Wt 485.59
Formula C27H31N7O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(4-Methoxy-2-(methyl(2-(methylamino)ethyl)amino)-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide

References

1. Finlay MR, et al. J Med Chem. 2014 Oct 23;57(20):8249-67.

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