Catalog No.: PC-63154Not For Human Use, Lab Use Only.
AZD-1305 is a novel antiarrhythmic agent that predominantly blocks the rapid component of IKr, the L-type calcium current, and the inward sodium current in mammalian cells and ventricular cardiomyocytes.
AZD-1305 is a novel antiarrhythmic agent that predominantly blocks the rapid component of IKr, the L-type calcium current, and the inward sodium current in mammalian cells and ventricular cardiomyocytes。
AZD-1305 significantly prolongs action potential duration and reduces excitability at 0.1-10 uM in dogs.
AZD-1305 effectively prevents induction of persistent acetylcholine-mediated atrial fibrillation (AF) in vivo.
