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AZD0095

Chemical Structure : AZD0095

CAS No.: 2750001-23-9

AZD0095 (AZD-0095)

Catalog No.: PC-49588Not For Human Use, Lab Use Only.

AZD0095 (AZD-0095) is a potent, selective monocarboxylate transporter 4 (MCT4) inhibitor with IC50 of 1.3 nM, >1000-fold selectivity over MCT1.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

AZD0095 (AZD-0095) is a potent, selective monocarboxylate transporter 4 (MCT4) inhibitor with IC50 of 1.3 nM, >1000-fold selectivity over MCT1.

Physicochemical Properties

M.Wt 500.607
Formula C27H32N8O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-4-((6-(4-(3-((2,5,7-trimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)oxy)pyrrolidin-1-yl)phenyl)pyridazin-3-yl)methyl)morpholine

References

1. Frederick W Goldberg, et al. J Med Chem. 2022 Dec 16. doi: 10.1021/acs.jmedchem.2c01342.

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